منابع مشابه
Estimation of clinical trial success rates and related parameters.
Previous estimates of drug development success rates rely on relatively small samples from databases curated by the pharmaceutical industry and are subject to potential selection biases. Using a sample of 406 038 entries of clinical trial data for over 21 143 compounds from January 1, 2000 to October 31, 2015, we estimate aggregate clinical trial success rates and durations. We also compute dis...
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Das diesem Bericht zugrundeliegende Forschungsvorhaben wurde mit Mitteln des Bundesministers f ur Bildung, Wissenschaft, Forschung und Technologie unter dem F orderkennzeichen 01 IV 102 F/4, 01 IV 101 V und 01 IV 102 H/0 gef ordert. Die Verantwortung f ur den Inhalt dieser Arbeit liegt bei den Au-toren. ABSTRACT We describe a number of experiments that demonstrate the usefulness of prosodic inf...
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Embryo implantation is critically dependent on a supportive uterine environment. Uterine receptivity is the culmination of a cellular and molecular transformation mediated locally by paracrine signals under the governance of ovarian steroid hormones, with cells and cytokines of the immune system playing integral roles in this process (1,2). The implantation rates and subsequent pregnancy rates ...
متن کاملSuccess Rates of Patients With Infantile Exotropia.
Infantile exotropia generally presents in a similar fashion to congenital esotropia. It typically occurs early in life and presents with a large, constant exodeviation. Patients with infantile exotropia are usually operated on early in life in the same manner as patients with congenital esotropia. In this issue, Rajavi et al. demonstrated that 18.3% of patients with infantile exotropia needed a...
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2016
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd.2016.136